抗ヒト Actinin-4 splice variant モノクローナル抗体

適用	(2.5μg/mL) (5μg/mL)
交差性
その他	//Function: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. //Subcellular location:Nucleus. Cytoplasm. //Tissue specificity: Widely expressed. //Sequence similarities: Belongs to the alpha-actinin family.
文献	Oncogene. 23: 5257-5262. 2004 Alternative splice variant of actinin-4 in small cell lung cancer Honda K, Yamada T, Seike M, Hayashida Y, Idogawa M, Kondo T, Ino Y, Hirohashi S. Annals of Oncology 00: 1-7. 2012 Diagnostic and prognostic significance of the alternatively spliced ACTN4 variant in high-grade neuroendocrine pulmonary tumours Miyanaga A, Honda K, Tsuta K, Masuda M, Yamaguchi U, Fujii G, Miyamoto A, Shinagawa S, Miura N, Tsuda H, Sakuma T, Asamura H, Gemma A, Yamada T.
共同研究	国立がん研究センター研究所山田哲司先生