抗マウス Fcα/μR モノクローナル抗体 (Clone No.TX57) KO571

適用	(5.0-10μg/mL) (5.0-10μg/mL) (0.5-1.0μg/mL)
交差性
その他	//Function: Functions as a receptor for the Fc fragment of IgA and IgM. Binds IgA and IgM with high affinity and mediates their endocytosis. May function in the immune response to microbes mediated by IgA and IgM. //Subcellular location: Cell membrane; Single-pass type I membrane protein. //Tissue specificity: Expressed in several tissues including thymus, spleen, liver, kidney, small and large intestine, testis and placenta. Expressed by oligodendrocytes, B cells and macrophages but not granulocytes, T cells or NK cells (at protein level). //Sequence similarities: Contains 1 Ig-like V-type (immunoglobulin-like) domain.
文献	Biochem Biophys Res Commun. 2006 Jun 23;345(1):474-8. Molecular characteristics of IgA and IgM Fc binding to the Fcalpha/muR. Cho Y, Usui K, Honda S, Tahara-Hanaoka S, Shibuya K, Shibuya A. Springer Semin Immunopathol. 2006 Dec;28(4):377-82. Epub 2006 Oct 24. Molecular and functional characteristics of the Fcalpha/muR, a novel Fc receptor for IgM and IgA. Shibuya A, Honda S
共同研究	筑波大学渋谷彰先生