Anti Human Klotho Monoclonal Antibody (Clone No. KM2119)
| Volume： | 50μg/200μL |
| Price： | inquiry |
 Data Sheet |
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| Antigen： | humanKlotho 801-954a.a. |
|---|---|
| GenBank ID： | 9365 |
| Immunizing animal： | rat |
| Purification： | ProteinG |
| Antibody subclass： | IgG2b |
| Application |  (1.0-5.0μg/mL)  (Availableμg/mL) |
|---|---|
| Cross React |   |
| Others | May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues atpositions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium andphosphorus homeostasis by inhibiting the synthesis of active vitamin D By similarity. Essential factor for the specific interactionbetween FGF23 and FGFR1 By similarity. The Klotho peptide generated by cleavage of the membrane-bound isoform may be an anti-aging circulating hormone which wouldextend life span by inhibiting insulin/IGF1 signaling By similarity. |
| Reference |
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| Collaborators | — |
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How to Order
Please contact one of following international distributors.
- Cosmo Bio USA, Inc.
- E-mail : info@cosmobiousa.com
TEL : +1-760-431-4600
FAX : +1-760-431-4600
- Funakoshi Corporation
- E-mail : reagent@funakoshi.co.jp
TEL : +81-3-5684-1620
FAX : +81-3-5684-1775
- FUJIFILM Wako Pure Chemical Corporation
- E-mail : ffwk-labchem-tec@fujifilm.com
TEL : 0120-052-099 (only in Japan)
FAX : 0120-052-806 (only in Japan)
- Sceti K.K.
- E-mail : export@sceti.co.jp
TEL : +81-3-5510-2652
FAX : +81-3-5510-0133