Anti Rat PERIOD3 Polyclonal Antibody
| Volume： | 200μg/200μL |
| Price： | inquiry |
 Data Sheet |
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| Antigen： | GST fusion protein |
|---|---|
| GenBank ID： | 78962 |
| Immunizing animal： | rabbit |
| Purification： | ProteinG |
| Antibody subclass： | – |
| Application |  (5.0-10.0μg/mL) |
|---|---|
| Cross React |  |
| Others | Most organisms show circadian 24-h rhythmicity in their behavior and phsysiology. In mammals, biological clock is located in the suprachiasmatic nucleus (SCN), generates circadian rhythms in behaviour and physiology. These biological rhythms are adjusted daily to the environmental light/dark cycle via the retinohypothalamic tract (RHT). Three mammalian priod genes (per1, per2, and per3) that resemble the clock-regulating gene of Dorosophia melangaster, period（per ）, have been cloned. Circadian clocks are also located in peripheral tissues of mammals that are synchronized by the SCN. A molecular description of the mammalian circadian system has revealed that circadian oscillations may be a fundamental property of many cells in the body. Recently, it has been shown that the phosphorylation of PER proteins by casein kinase Iε can modulate the nuclear localization of mPER1 and mPER3 but not of mPER2 This antibody is useful tool to clarify molecular functions that regulate biological clock. |
| Reference | — |
| Collaborators | Dr. Norio Ishida Advanced industrial science and technology |
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How to Order
Please contact one of following international distributors.
- Cosmo Bio USA, Inc.
- E-mail : info@cosmobiousa.com
TEL : +1-760-431-4600
FAX : +1-760-431-4600
- Funakoshi Corporation
- E-mail : reagent@funakoshi.co.jp
TEL : +81-3-5684-1620
FAX : +81-3-5684-1775
- FUJIFILM Wako Pure Chemical Corporation
- E-mail : ffwk-labchem-tec@fujifilm.com
TEL : 0120-052-099 (only in Japan)
FAX : 0120-052-806 (only in Japan)
- Sceti K.K.
- E-mail : export@sceti.co.jp
TEL : +81-3-5510-2652
FAX : +81-3-5510-0133