Antibody Products

Product NameAnti Mouse Trpm7 Polyclonal Antibody

Cat. No.:
KO464
sample

Volume: 25μg/100μL
Price: inquiry
Data Sheet Data Sheet
Antigen: partial peptide
GenBank ID: 58800
Immunizing animal: rabbit
Purification: Antigen Affinity
Antibody subclass:
Application ELISA(1.0μg/mL)
Cross React Human Mouse
Others //Function: Essential ion channel and serine/threonine-proteinkinase. Divalent cation channel permeableto calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1).
//Tissue specificity: Found to be expressed in brain and skeletal muscle, with stronger signals in kidney, heart, liver and spleen.
//Sequence similarities: In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily. In the N-terminal section; belongs to the transient receptor family. LTrpC subfamily. Contains 1 alpha-type protein kinase domain.
Reference
  • J Pharmacol Sci. 2004 Aug;95(4):403-19.
    Involvement of TRPM7 in cell growth as a spontaneously activated Ca2+ entry pathway in human retinoblastoma cells.
    Hanano T, Hara Y, Shi J, Morita H, Umebayashi C, Mori E, Sumimoto H, Ito Y, Mori Y, Inoue R.
Collaborators Dr. Yasuo Mori, Kyoto University

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Cosmo Bio USA, Inc.
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