Antibody Products

Product NameAnti Mouse Trpm2 Polyclonal Antibody

Cat. No.:
KO462
sample

Volume: 25μg/100μL
Price: inquiry
Data Sheet Data Sheet
Antigen: partial peptide
GenBank ID: 28240
Immunizing animal: rabbit
Purification: Antigen Affinity
Antibody subclass:
Application ELISA(1.0μg/mL) Immuno CytoChemistry(1.0-5.0μg/mL)
Cross React Mouse
Others //Function: Nonselective, voltage-independentcation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellularcalcium passes through the channel and acts from the intracellularside as a positive regulator in channel activation.Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD+), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Has ADP-ribose pyrophosphatase activity.
//Tissue specificity: Widely expressed, with highest levels in lung, spleen, eye and brain.
//Sequence similarities: Belongs to the transient receptor family. LTrpC subfamily. Contains 1 nudix hydrolase domain.
Reference
  • J Pharmacol Sci. 2006 May;101(1):66-76.
    A critical role of TRPM2 in neuronal cell death by hydrogen peroxide.
    Kaneko S, Kawakami S, Hara Y, Wakamori M, Itoh E, Minami T, Takada Y, Kume T, Katsuki H, Mori Y, Akaike A.
Collaborators Dr. Yasuo Mori, Kyoto University

icon icon

How to Order

Please contact one of following international distributors.

Cosmo Bio USA, Inc.
E-mail : info@cosmobiousa.com
TEL : +1-760-431-4600
FAX : +1-760-431-4600
Funakoshi Corporation
E-mail : reagent@funakoshi.co.jp
TEL : +81-3-5684-1620
FAX : +81-3-5684-1775
FUJIFILM Wako Pure Chemical Corporation
E-mail : ffwk-labchem-tec@fujifilm.com
TEL : 0120-052-099 (only in Japan)
FAX : 0120-052-806 (only in Japan)
Sceti K.K.
E-mail : export@sceti.co.jp
TEL : +81-3-5510-2652
FAX : +81-3-5510-0133