Antibody Products

Product NameAnti Mouse Trpc6 Polyclonal Antibody

Cat. No.:
KO460
sample

Volume: 25μg/100μL
Price: inquiry
Data Sheet Data Sheet
Antigen: partial peptide
GenBank ID: 22068
Immunizing animal: rabbit
Purification: Antigen Affinity
Antibody subclass:
Application ELISA(1.0μg/mL) Immuno CytoChemistry(1.0-5.0μg/mL) Immuno HistoChemistry(5.0-10μg/mL)
Cross React Mouse Other
Others //Function: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.
//Tissue specificity: Lung and brain. Post-translational modification: N-glycosylated.
//Sequence similarities: Belongs to the transient receptor family. STrpC subfamily. Contains 3 ANK repeats.
Reference
  • Circ Res. 2001 Feb 16;88(3):325-32.
    The transient receptor potential protein homologue TRP6 is the essential component of vascular alpha(1)-adrenoceptor-activated Ca(2+)-permeable cation channel.
    Inoue R, Okada T, Onoue H, Hara Y, Shimizu S, Naitoh S, Ito Y, Mori Y.
Collaborators Dr. Yasuo Mori, Kyoto University

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