Antibody Products

Product NameAnti Rat TRPV2 (VRL-1) Polyclonal Antibody

Cat. No.:
KM019
KM019

Volume: 5μg/50μL
Price: inquiry
Data Sheet Data Sheet
Antigen: partial peptide
GenBank ID: 29465
Immunizing animal: rabbit
Purification: Antigen Affinity
Antibody subclass:
Application Immuno HistoChemistry(0.1μg/mL)
Cross React Rat
Others TRPV2 (transient receptor potential cation channel, subfamily V, member 2) gene is isolated as a homologue of vanilloid receptor, VR-1 (now named TRPV1). TRPV2 is supposed to be an ion channel which has 6 transmembrane regions. And it’s obvious that TRPV2 is activated by heat more than 50℃, not by vanilloids (capsaicin and RTX) or protons.
It is thought that myelinated Aδfiber have heat sensitivity neuron with temperature threshold of 52 ℃. TRPV2 is proved to exist in myelinated Aδfiber by immunohistochemistry.
This polyclonal antibody is specific for TRPV2 of rat, and has been proved to be useful for the immunohistochemistry.
Reference
  • J Neurosci. 2010 Mar 31;30(13):4601-12.
    TRPV2 enhances axon outgrowth through its activation by membrane stretch in developing sensory and motor neurons.
    Shibasaki K, Murayama N, Ono K, Ishizaki Y, Tominaga M.
Collaborators Dr. Tominaga, M. Department of Physiology, Faculty of Medicine, Mie University, Japan

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How to Order

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Cosmo Bio USA, Inc.
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TEL : +1-760-431-4600
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Funakoshi Corporation
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FUJIFILM Wako Pure Chemical Corporation
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Sceti K.K.
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