Antibody Products

Product NameAnti bovine NR5A1 Polyclonal Antibody

Cat. No.:
KO611
sample

Volume: 50μg/200μL
Price: inquiry
Data Sheet Data Sheet
Antigen: recombinant protein (full-length)
GenBank ID: 281948
Immunizing animal: rabbit
Purification: ProteinG
Antibody subclass:
Application ELISA(1.0μg/mL) Western Blotting(1.0-5.0μg/mL) Immuno Precipitation(5.0-10μg/mL) Immuno CytoChemistry(1.0-5.0μg/mL) Immuno HistoChemistry(1.0-2.0μg/mL)
Cross React Mouse
Others Transcriptional activator. Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5′-YCAAGGYC-3′ and 5′-RRAGGTCA-3′ are the consensus sequences for the recognition by NR5A1. The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional avtivity. Binds phospholipids with a phosphatidylinositol (PI) headgroup, in particular PI(3,4)P2 and PI(3,4,5)P3.
Reference
  • J Biochem.1998 Jul;124(1):217-24.
    Adrenocortical and gonadal expression of the mammalian Ftz-F1 gene encoding Ad4BP/SF-1 is independent of pituitary control.
    Nomura M, Kawabe K, Matsushita S, Oka S, Hatano O, Harada N, Nawata H, Morohashi K.
Collaborators

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How to Order

Please contact one of following international distributors.

Cosmo Bio USA, Inc.
E-mail : info@cosmobiousa.com
TEL : +1-760-431-4600
FAX : +1-760-431-4600
Funakoshi Corporation
E-mail : reagent@funakoshi.co.jp
TEL : +81-3-5684-1620
FAX : +81-3-5684-1775
FUJIFILM Wako Pure Chemical Corporation
E-mail : ffwk-labchem-tec@fujifilm.com
TEL : 0120-052-099 (only in Japan)
FAX : 0120-052-806 (only in Japan)
Sceti K.K.
E-mail : export@sceti.co.jp
TEL : +81-3-5510-2652
FAX : +81-3-5510-0133