Antibody Products

Product NameAnti Human Siah 2 Polyclonal Antibody

Cat. No.:
KR056
KR056

Volume: 25μg/100μL
Price: inquiry
Data Sheet Data Sheet
Antigen: partial peptide
GenBank ID: 6478
Immunizing animal: rabbit
Purification: Antigen Affinity
Antibody subclass:
Application Western Blotting(0.2μg/mL)
Cross React Human
Others The turnover of a protein is precisely under control in the cell. Particularly, the system of controlling protein degradation via the ubiquitin-proteosome pathway is involving in many kinds of process in the cell. The Drosophila Seven in absentina (Sina) gene product originally was identified as a protein that controls cell fate decisions during eye development. Its mammalian homolog, Siah1 and Siah2, have been described that they might involve in ubiquitin-mediated proteolysis of several proteins, as well as in growth arrest and p53-induced apoptosis. Siah2 is expressed in olfactory epithelium, retina, forebrain and proliferating cartilage of developing bone by mRNA level.
This antibody is very useful for identifying the function of the mammalian Siah2 in the cell.
Reference
  • Cancer Res. 2006 Oct 15;66(20):9870-7.
    EBV latent membrane protein 1 up-regulates hypoxia-inducible factor 1alpha through Siah1-mediated down-regulation of prolyl hydroxylases 1 and 3 in nasopharyngeal epithelial cells.
    Kondo S, Seo SY, Yoshizaki T, Wakisaka N, Furukawa M, Joab I, Jang KL, Pagano JS.
Collaborators Dr.Koki Moriyoshi at Department of Biological Sciences, Kyoto University Faculty of Medicine

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How to Order

Please contact one of following international distributors.

Cosmo Bio USA, Inc.
E-mail : info@cosmobiousa.com
TEL : +1-760-431-4600
FAX : +1-760-431-4600
Funakoshi Corporation
E-mail : reagent@funakoshi.co.jp
TEL : +81-3-5684-1620
FAX : +81-3-5684-1775
FUJIFILM Wako Pure Chemical Corporation
E-mail : ffwk-labchem-tec@fujifilm.com
TEL : 0120-052-099 (only in Japan)
FAX : 0120-052-806 (only in Japan)
Sceti K.K.
E-mail : export@sceti.co.jp
TEL : +81-3-5510-2652
FAX : +81-3-5510-0133