Anti Human CD71(TFRC) Monoclonal Antibody (Clone No.YUK9)
| Volume： | 50μg/200μL |
| Price： | inquiry |
 Data Sheet |
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| Antigen： | human cancer cel line |
|---|---|
| GenBank ID： | 7073 |
| Immunizing animal： | mouse |
| Purification： | ProteinG |
| Antibody subclass： | IgG1κ |
| Application |  (5.0-10.0μg/mL)  (1.0-5.0μg/mL) |
|---|---|
| Cross React |  |
| Others | CD71 (also known as TFRC: transferrin receptor) is a widely expressed 180 kDa type II membrane glycoprotein involved in the cellular uptake of iron and in the regulation of cell growth. Iron uptake occurs via the internalization of iron-loaded transferrin mediated by the interaction with the CD71. CD71 expression is increased on rapidly proliferating cells, while expression is decreased or absent on non-dividing cells. Some studies have suggested that biologically aggressive tumors require large amounts of iron for active metabolism and rapid cell growth, and overexpression of CD71 has reported in different types of cancers such as glioma, pancreatic, and colon cancers. In addition, CD71 is required for adult erythropoiesis and involved in T- and B- cell development. CD71 seems to play an important role in T cell activation, and T cells lacking CD71 are completely arrested at a very early stage of maturation. This antibody is specific to human CD71 and will be useful for FCM, immunoprecipitation. |
| Reference | — |
| Collaborators | Dr. Kato K. Sapporo medical university |
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How to Order
Please contact one of following international distributors.
- Cosmo Bio USA, Inc.
- E-mail : info@cosmobiousa.com
TEL : +1-760-431-4600
FAX : +1-760-431-4600
- Funakoshi Corporation
- E-mail : reagent@funakoshi.co.jp
TEL : +81-3-5684-1620
FAX : +81-3-5684-1775
- FUJIFILM Wako Pure Chemical Corporation
- E-mail : ffwk-labchem-tec@fujifilm.com
TEL : 0120-052-099 (only in Japan)
FAX : 0120-052-806 (only in Japan)
- Sceti K.K.
- E-mail : export@sceti.co.jp
TEL : +81-3-5510-2652
FAX : +81-3-5510-0133