Anti Human CD59(HRF20) Monoclonal Antibody (Clone No.YUK1)
| Volume： | 50μg/200μL |
| Price： | inquiry |
 Data Sheet |
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| Antigen： | human cancer cel line |
|---|---|
| GenBank ID： | 966 |
| Immunizing animal： | mouse |
| Purification： | ProteinG |
| Antibody subclass： | IgG1κ |
| Application |  (5.0-10.0μg/mL)  (5.0-10.0μg/mL) |
|---|---|
| Cross React |  |
| Others | CD59 (also known as HRF20: 20KDa-Homologous restriction factor) is an about 20 kDa glycoprotein and member of membrane-bound complement-regulatory protein (CRP), and prevents formation of the membrane attack complex (MAC) in the terminal stages of complement activation. CRPs inhibit complement-mediated killing of host cells by host complement. It has been also showed that p53 regulates cellular resistance to complement lysis through enhanced expression of CD59. CRPs are often elevated in malignancy, and enable tumor cells to escape from complement-dependent cytotoxicity. Therefore, expression, overexpression, or loss of these molecules may function as markers of tumor progression and prognosis. This antibody is specific to human CD59 and will be useful for FCM, immunoprecipitation. |
| Reference | — |
| Collaborators | Dr. Kato K. Sapporo medical university |
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How to Order
Please contact one of following international distributors.
- Cosmo Bio USA, Inc.
- E-mail : info@cosmobiousa.com
TEL : +1-760-431-4600
FAX : +1-760-431-4600
- Funakoshi Corporation
- E-mail : reagent@funakoshi.co.jp
TEL : +81-3-5684-1620
FAX : +81-3-5684-1775
- FUJIFILM Wako Pure Chemical Corporation
- E-mail : ffwk-labchem-tec@fujifilm.com
TEL : 0120-052-099 (only in Japan)
FAX : 0120-052-806 (only in Japan)
- Sceti K.K.
- E-mail : export@sceti.co.jp
TEL : +81-3-5510-2652
FAX : +81-3-5510-0133