Antibody Products

Product NameAnti Rabbit Macrophage/Monocyte Monoclonal Antibody ( Clone No. RbM2 )

Cat. No.：
KT015
KT015

Volume： 50μg/200μL
Price： inquiry
Data Sheet Data Sheet
Antigen： rabbit peritoneal macrophage
GenBank ID： –
Immunizing animal： mouse
Purification： ProteinG
Antibody subclass： IgG1
Application Immuno HistoChemistry(10μg/mL)
Cross React Other
Others This anti-rabbit macrophage monoclonal antibody, RbM2, was produced by using thiogllycate-elicited rabbit peritoneal macrophages as immunogen. Immunoelectoron microscopy demonstrates that RbM2 reacts with lysosomes of rabbit macrophages and monocytes. This selective reactivity was confirmed in various experiments by endocytosis. In contrast, dendritic cells, such as follicular dendritic cells (FDCs) of
lymphoid follicles, interdigitating cells(IDCs) of lymphoid T zone, or epidermal Langerhan’s cells, are not reactive with this antibody.
The antigen recognized by RbM2 is a lysosomal membrane protein with 50,000 molecular weight.
Thus, this antibody is very useful for not only in discriminating monocyte / macrophages from various cell populations but also in identifying lysosomes and their related structures in macrophages.
Reference
  • Immunology. 1990 Aug;70(4):513-9.
    A monoclonal antibody, RbM2, specific for a lysosomal membrane antigen of rabbit monocyte/macrophages.
    Shimokawa Y, Takeya M, Miyauchi Y, Takahashi K.

  • Spine (Phila Pa 1976). 2005 Jan 1;30(1):55-61.
    Intervertebral disc cells produce tumor necrosis factor alpha, interleukin-1beta, and monocyte chemoattractant protein-1 immediately after herniation: an experimental study using a new hernia model.
    Yoshida M, Nakamura T, Sei A, Kikuchi T, Takagi K, Matsukawa A.

  • J Vasc Surg. 2009 Dec;50(6):1433-43.
    Gene transduction into aortic wall using plasmid-loaded cationized gelatin hydrogel-coated polyester stent graft.
    Zhong H, Matsui O, Xu K, Ogi T, Sanada J, Okamoto Y, Tabata Y, Takuwa Y.
Collaborators Dr. Takeya M., Second Department of Pathology, Kumamoto University School of Medicine, Kumamoto, Japan

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How to Order

Please contact one of following international distributors.

Cosmo Bio USA, Inc.
E-mail : info@cosmobiousa.com
TEL : +1-760-431-4600
FAX : +1-760-431-4600
Funakoshi Corporation
E-mail : reagent@funakoshi.co.jp
TEL : +81-3-5684-1620
FAX : +81-3-5684-1775
FUJIFILM Wako Pure Chemical Corporation
E-mail : ffwk-labchem-tec@fujifilm.com
TEL : 0120-052-099 (only in Japan)
FAX : 0120-052-806 (only in Japan)
Sceti K.K.
E-mail : export@sceti.co.jp
TEL : +81-3-5510-2652
FAX : +81-3-5510-0133