Antibody Products

Product NameAnti Rat Macrophage/Dendritic Cells Monoclonal Antibody ( Clone No. RM-4 )

Cat. No.：
KT014
KT014

Volume： 50μg/200μL
Price： inquiry
Data Sheet Data Sheet
Antigen： rat pulmonary granuloma homogenate
GenBank ID： –
Immunizing animal： mouse
Purification： ProteinG
Antibody subclass： IgG1
Application Immuno HistoChemistry(10μg/mL)
Cross React Rat
Others This anti-rat macrophage/dendritic cells monoclonal antibody, RM-4, was produced by using a homogenate of silica-induced lung granulomas of rat as immunogen. Immunohistochemistry demonstrated that RM-4 is specific for rat macrophages and dendritic cell populations in various organs and tissues.
In both cryostat sections and formalin-fixed paraffin sections, this antibody recognizes the antigen, of which molecular weight is 46kDa, presenting on the membrane of endosomes and lysosomes in macrophages and dendrictic cells.
Thus, this antibody is very useful for not only in discriminating macrophage/dendritic cells from various cell populations but also in identifying endosomes and lysosomes.
Reference
  • Histochem J. 1997 Feb;29(2):105-16.
    A novel monoclonal antibody, RM-4, specifically recognizes rat macrophages and dendritic cells in formalin-fixed, paraffin-embedded tissues.
    Iyonaga K, Takeya M, Yamamoto T, Ando M, Takahashi K.

  • Wound Repair Regen. 2007 Jan-Feb;15(1):87-93.
    Bone marrow-derived myofibroblasts recruited to the upper dermis appear beneath regenerating epidermis after deep dermal burn injury.
    Yamaguchi R, Takami Y, Yamaguchi Y, Shimazaki S.

  • J Cell Physiol. 2008 Jun;215(3):837-45.
    Platelet-rich plasma enhances the initial mobilization of circulation-derived cells for tendon healing.
    Kajikawa Y, Morihara T, Sakamoto H, Matsuda K, Oshima Y, Yoshida A, Nagae M, Arai Y, Kawata M, Kubo T.

  • J Pathol. 2009 Jul;218(3):350-9.
    Enhancing epithelial engraftment of rat mesenchymal stem cells restores epithelial barrier integrity.
    Yabana T, Arimura Y, Tanaka H, Goto A, Hosokawa M, Nagaishi K, Yamashita K, Yamamoto H, Adachi Y, Sasaki Y, Isobe M, Fujimiya M, Imai K, Shinomura Y.

  • Toxicol Pathol. 2009;37(5):599-605.
    Histological and immunohistochemical studies on spontaneous rat astrocytomas and malignant reticulosis.
    Nagatani M, Ando R, Yamakawa S, Saito T, Tamura K.

  • J Hypertens. 2010 Jun;28(6):1273-80.
    LOX-1 mediates vascular lipid retention under hypertensive state.
    Nakano A, Inoue N, Sato Y, Nishimichi N, Takikawa K, Fujita Y, Kakino A, Otsui K, Yamaguchi S, Matsuda H, Sawamura T.

  • J Gastroenterol.Feb;46(2):143-52.
    Myogenic lineage differentiated mesenchymal stem cells enhance recovery from dextran sulfate sodium-induced colitis in the rat.
    Tanaka H, Arimura Y, Yabana T, Goto A, Hosokawa M, Nagaishi K, Yamashita K, Yamamoto H, Sasaki Y, Fujimiya M, Imai K, Shinomura Y.
Collaborators Dr. Takeya M., Second Department of Pathology, Kumamoto University School of Medicine, Kumamoto, Japan

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How to Order

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Cosmo Bio USA, Inc.
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TEL : +1-760-431-4600
FAX : +1-760-431-4600
Funakoshi Corporation
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FUJIFILM Wako Pure Chemical Corporation
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Sceti K.K.
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FAX : +81-3-5510-0133