Anti Rat MARCKS Monoclonal Antibody ( Clone No. MAR 11/2 )
| Volume： | 50μg/200μL |
| Price： | inquiry |
 Data Sheet |
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| Antigen： | partial peptide |
|---|---|
| GenBank ID： | 25603 |
| Immunizing animal： | rat |
| Purification： | ProteinG |
| Antibody subclass： | IgG2a |
| Application |  (1.0-5.0μg/mL) |
|---|---|
| Cross React |  |
| Others | Myristoylated alanine-rich C kinase substrate (MARCKS), a specific substrate for protein kinase C, is abundant in the brain. MARCKS binds calmodulin under Ca2+ or actin under non-Ca2+ conditions. Phosphorylation of MARCKS (P-MARCKS) can be used as an indicator of protein kinase C activation in intact cells. It has been shown that P-MARCKS has relatively weaker binding activity to calmodulin and actin compared with MARCKS. Pathophysiologically, P-MARCS is also detected in the brain of Alzheimer’s disease patients and in the smooth muscle cells of arteriosclerosis. This antibody is specific to MARCKS and could be used for western blotting and immunohistchemistry. |
| Reference | — |
| Collaborators | — |
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How to Order
Please contact one of following international distributors.
- Cosmo Bio USA, Inc.
- E-mail : info@cosmobiousa.com
TEL : +1-760-431-4600
FAX : +1-760-431-4600
- Funakoshi Corporation
- E-mail : reagent@funakoshi.co.jp
TEL : +81-3-5684-1620
FAX : +81-3-5684-1775
- FUJIFILM Wako Pure Chemical Corporation
- E-mail : ffwk-labchem-tec@fujifilm.com
TEL : 0120-052-099 (only in Japan)
FAX : 0120-052-806 (only in Japan)
- Sceti K.K.
- E-mail : export@sceti.co.jp
TEL : +81-3-5510-2652
FAX : +81-3-5510-0133