Anti Human CD298(Na/K-ATPase b3) Monoclonal Antibody (Clone No.5G10)
| Volume： | 50μg/200μL |
| Price： | inquiry |
 Data Sheet |
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| Antigen： | human cancer cel line |
|---|---|
| GenBank ID： | 483 |
| Immunizing animal： | mouse |
| Purification： | ProteinG |
| Antibody subclass： | IgG2aκ |
| Application |  (5.0-10.0μg/mL)  (5.0-10.0μg/mL)  (0.5-1.0μg/mL) |
|---|---|
| Cross React |  |
| Others | Na/K-ATPase is a membrane-associated enzyme responsible for the active transport of Na + and K+, and the maintenance of Na+ and K+ gradients across membrane. It is a heterodimer of two different kinds subunit, a large α subunit and a smaller glycoprotein subunit β. At least four distinct α subunit and four β subunit isoforms have been identified. In some tissues, it has been showed that Na/K-ATPase is associated with third subunit γ, a small regulatory protein. CD298 (also known as Na/K-ATPase β3) is a 42-kDa glycoprotein and one of β subunit isoforms. CD298 has been detected in amphibians, mouse, rat, and human. In rat, CD298 expresses in a variety of tissues including testis, brain, kidney, spleen, stomach, small intestine, colon, lung, and liver. In the retina Na/K-ATPase restores Na+ and K+ gradients used by photoreceptor dark current, synaptic activity, action potential, and CD298 is largely restricted to photoreceptors in the mouse and rat. In human, CD298 also involves in regulation of T and B lymphocyte proliferation. This antibody is specific to human CD298 and will be useful for FCM, immunoprecipitation, immunohistochemistry. |
| Reference | — |
| Collaborators | Dr. Kato K. Sapporo medical university |
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How to Order
Please contact one of following international distributors.
- Cosmo Bio USA, Inc.
- E-mail : info@cosmobiousa.com
TEL : +1-760-431-4600
FAX : +1-760-431-4600
- Funakoshi Corporation
- E-mail : reagent@funakoshi.co.jp
TEL : +81-3-5684-1620
FAX : +81-3-5684-1775
- FUJIFILM Wako Pure Chemical Corporation
- E-mail : ffwk-labchem-tec@fujifilm.com
TEL : 0120-052-099 (only in Japan)
FAX : 0120-052-806 (only in Japan)
- Sceti K.K.
- E-mail : export@sceti.co.jp
TEL : +81-3-5510-2652
FAX : +81-3-5510-0133