Anti Human CD98hc(4F2) Monoclonal Antibody (Clone No.WK4)
| Volume： | 50μg/200μL |
| Price： | inquiry |
 Data Sheet |
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| Antigen： | human cancer cel line |
|---|---|
| GenBank ID： | 6520 |
| Immunizing animal： | mouse |
| Purification： | ProteinG |
| Antibody subclass： | IgG2aκ |
| Application |  (5.0-10.0μg/mL)  (0.5-1.0μg/mL) |
|---|---|
| Cross React |  |
| Others | CD98 (also known as 4F2) is widely expressed cell surface around 120-kDa heterodimetric protein. CD98 is composed a common type II transmembrane heavy chain of around 80-kDa (also kwon as CD98hc, 4F2hc or SLC3A2) and one of at least six light chains of around 40-kDa (LAT1, LAT2, y+LAT1, y+LAT2, xCT, asc) to form amino acid transporters. It is thought that the heavy chain is mainly involved in the trafficking of the complex to the plasma membrane, whereas the light chain catalyses the transport itself. CD98hc is a multifunctional glycoprotein, and was originally discovered as a T-cell activation antigen. CD98hc is highly expressed on proliferating lymphocytes, tumor cells and on the other rapidly-growing cells. It has also shown that CD98hc has an important role in integrin-dependent signals that promote tumorigenesis. This antibody is specific to human CD98hc and will be useful for FCM, immunoprecipitation. |
| Reference | — |
| Collaborators | Dr. Kato K. Sapporo medical university |
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How to Order
Please contact one of following international distributors.
- Cosmo Bio USA, Inc.
- E-mail : info@cosmobiousa.com
TEL : +1-760-431-4600
FAX : +1-760-431-4600
- Funakoshi Corporation
- E-mail : reagent@funakoshi.co.jp
TEL : +81-3-5684-1620
FAX : +81-3-5684-1775
- FUJIFILM Wako Pure Chemical Corporation
- E-mail : ffwk-labchem-tec@fujifilm.com
TEL : 0120-052-099 (only in Japan)
FAX : 0120-052-806 (only in Japan)
- Sceti K.K.
- E-mail : export@sceti.co.jp
TEL : +81-3-5510-2652
FAX : +81-3-5510-0133