Anti Rat Organic Cation Transporter 3 Polyclonal Antibody
| Volume： | 25μg/100μL |
| Price： | inquiry |
 Data Sheet |
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| Antigen： | partial peptide |
|---|---|
| GenBank ID： | 29504 |
| Immunizing animal： | rabbit |
| Purification： | Antigen Affinity |
| Antibody subclass： | – |
| Application |  (1.0-5.0μg/mL) |
|---|---|
| Cross React |  |
| Others | To eliminate the drug, xenobiotics, a varirety of endogeneous substances, and their metabolites out of the body, specific membrane proteins named transporters are required. There are two major pathways for the elimination, one of which is hepatic one through bile, and another is renal one to urine. The transporter fall into various transport systems by the transportative substrate. In particular, oraganic ion transporter family is comprised of organic anion transport family (OAT), oraganic cation transport family (OCT), OCTN/carnitine transport family, and OAT are multispecific organic anion transpoters, the substrates of which include a lot of both endogeneous and exogeneous anions. Organic Cation Transporter 3 （OCT3） is expressed in kidney, placenta and brain. In brain, OCT3 is suggested that it is involved in monoamine regulation mechanism and plays a significant role in the disposition of cationic neurotoxins. This antibody was established from the purified serum immunized with partial peptide of rat OCT3. This antibody is useful for Immnohistochemistry. |
| Reference |
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| Collaborators | Dr. Takeda H. and Dr.Inazu M. at Department of Pharmacology, Tokyo Medical University |
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How to Order
Please contact one of following international distributors.
- Cosmo Bio USA, Inc.
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FAX : +1-760-431-4600
- Funakoshi Corporation
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- FUJIFILM Wako Pure Chemical Corporation
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TEL : 0120-052-099 (only in Japan)
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- Sceti K.K.
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TEL : +81-3-5510-2652
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