Anti Human Organic Anion Transporter 1(OAT1) Polyclonal Antibody
| Volume： | 25μg/250μL |
| Price： | inquiry |
 Data Sheet |
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| Antigen： | partial peptide |
|---|---|
| GenBank ID： | 9356 |
| Immunizing animal： | rabbit |
| Purification： | Antigen Affinity |
| Antibody subclass： | – |
| Application |  (5μg/mL) |
|---|---|
| Cross React |  |
| Others | To eliminate the drug, xenobiotics, a varirety of endogeneous substances, and their metabolites out of the body, specific membrane proteins named transporters are required. There are two major pathways for the elimination, hepatic one through bile and renal one to urine. The transporter fall into various transport systems by the transportative substrate. In particular, oraganic ion transporter family is comprised of organic anion transport family (OAT), oraganic cation transport family (OCT), OCTN/carnitine transport family, and OAT are multispecific organic anion transpoters, the substrates of which include a lot of both endogeneous and exogeneous anions . Human Organic anion transporter 1(OAT1) encodes a 563 amino acid residue protein, and which is predicted 12 putative membrane-spanning protein. Human OAT1 was found to be expressed predominantly in the kidney and only weakly in the brain. OAT1 mediates the Na+-independent transport of organic anions, such as PAH (ρ-aminohippurate), cyclic nucleotides, prostanoides, dicaroxylates, and many anion drugs. This antibody has been proved to be useful for immunohistochemistry. |
| Reference | — |
| Collaborators | — |
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How to Order
Please contact one of following international distributors.
- Cosmo Bio USA, Inc.
- E-mail : info@cosmobiousa.com
TEL : +1-760-431-4600
FAX : +1-760-431-4600
- Funakoshi Corporation
- E-mail : reagent@funakoshi.co.jp
TEL : +81-3-5684-1620
FAX : +81-3-5684-1775
- FUJIFILM Wako Pure Chemical Corporation
- E-mail : ffwk-labchem-tec@fujifilm.com
TEL : 0120-052-099 (only in Japan)
FAX : 0120-052-806 (only in Japan)
- Sceti K.K.
- E-mail : export@sceti.co.jp
TEL : +81-3-5510-2652
FAX : +81-3-5510-0133