Antibody Products

Product NameAnti Rat 4F2 Heavy Chain (4F2hc:CD98) Polyclonal Antibody

Cat. No.:
KE028
KE028

Volume: 25μg/250μL
Price: inquiry
Data Sheet Data Sheet
Antigen: partial peptide
GenBank ID: 50567
Immunizing animal: rabbit
Purification: Antigen Affinity
Antibody subclass:
Application Western Blotting(0.1-1.0μg/mL) Immuno HistoChemistry(5.0-10.0μg/mL)
Cross React Rat
Others Mammalian amino acid transport system is consisted of large variety of transporters, with the reflection of amoino acid molecule variety, and is classfied into various transport systems by the transportative substrate selectivity and the Na+ dependence with the reflection of amino acid molecule variety.
4F2 heavy chain(4F2hc:CD98)is originally identified as a cell-surface antigen which is upregulated by lymphocyte activation, and is a single memblane-spanning protein, of which molecular weight is under 85-kDa .The transporter corresponds to the amino acid transporter, system L, y+L, X-c, and asc, which requires 4F2hc for its functional expression. 4F2hc and its associated transporters are linked via disulfide band to form heterodimeric complexes. 4F2hc is present at cell membrane in blood vessel side of epitherliocyte, and transports its associated transporters to cell membrane of blood vessel in epitherliocyte.
This antidody has been proved to be useful for immunohistochemistry and immunoblotting.
Considering the peptide amino acid sequence, this antibody also seems to react with mouse 4F2hc.
Reference
  • Acta Neurochir Suppl. 2008;102:385-8.
    Up-regulation of L type amino acid transporter 1 after spinal cord injury in rats.
    Toyooka T, Nawashiro H, Shinomiya N, Yano A, Ooigawa H, Ohsumi A, Uozumi Y, Yanagawa Y, Matsuo H, Shima K.
Collaborators

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How to Order

Please contact one of following international distributors.

Cosmo Bio USA, Inc.
E-mail : info@cosmobiousa.com
TEL : +1-760-431-4600
FAX : +1-760-431-4600
Funakoshi Corporation
E-mail : reagent@funakoshi.co.jp
TEL : +81-3-5684-1620
FAX : +81-3-5684-1775
FUJIFILM Wako Pure Chemical Corporation
E-mail : ffwk-labchem-tec@fujifilm.com
TEL : 0120-052-099 (only in Japan)
FAX : 0120-052-806 (only in Japan)
Sceti K.K.
E-mail : export@sceti.co.jp
TEL : +81-3-5510-2652
FAX : +81-3-5510-0133